Southern Airlines is a fictional airline seen in the Movie "Random Hearts". In the movie's plot the airline suffers a crash on a flight to Miami and all aboard die. The rest of the movie is alot of drama from the death of 2 spouse's loved ones in the crash. Not much else is known about the airline. There is a real southern airlines as well, but they have no connection whatsoever.
The crashed aircraft was a 737, but it is also shown to operate 747s as seen in a Scale model.